Archive

Project Summary: Every 20 minutes someone in Australia suffers a stroke and approximately half of the stroke survivors have spatial neglect [1]. Persons suffering from spatial neglect are not paying attention to the space opposite of their brain lesion and severe forms of neglect lead to...

Project Summary: Alzheimer’s disease (AD) is the most common form of dementia, affecting ~30% of the elderly population over 75. Although classic symptoms include a decline in memory, the condition is only truly diagnosed at autopsy based on the presence of pathological features known as amyloid-beta...

Project Summary: Brain arteriovenous malformations (AVMs) are abnormalities of blood vessels, in which direct connections form between arteries and veins. The high-pressure arterial blood injects into fragile cerebral veins and leads to a high risk of brain haemorrhage and stroke. AVMs occur in approximately 0.1% of...

Project Summary: As the brain ages it takes on a pro-inflammatory profile associated with priming of immune cells so that they become hyper-active. Aged individuals, even otherwise healthy ones, therefore respond to illness and infection with exaggerated immune responses that can be fatal. The brain’s immune...

Project Summary: Cerebral carnevous malformation (CCM), also known as Angioma or Cavernoma, is a cerebrovascular disease which affects the blood vessels supplying the brain and is the leading cause of strokes in young patients. The disease causes collections of abnormal vessels to form throughout the brain,...

Project Summary: Aging causes our cells to decline in both integrity and function. As such, the incidence of disorders that affect nerve cells, including Alzheimer’s disease (AD), increases with aging. In healthy cells, our genes are tightly regulated so that the correct combination of genes are...

Project Summary: Stroke is among the top ten causes of death in children and is more common than brain tumours. Contrary to popular belief, children do not recover better than adults because more than half of childhood stroke survivors have long term disabilities, which may include...

Project Summary: Dementia is an increasing epidemic currently affecting some 321,600 people in Australia, with a projected increase to 553,285 by 2030 and 942,624 by mid century. The economic impact of dementia on the health care system and community is considerable. Alzheimer's disease is the most...

Project Summary: There is a critical need for inexpensive, individualised rehabilitation interventions that improve motor function in stroke patients. Each year 15 million people worldwide suffer a stroke, and in one third of cases, the stroke results in permanent disability [1]. Long-term impairment to motor function...

Project Summary: Obstructive Sleep Apnoea (OSA) is a highly prevalent chronic illness, characterised by repetitive collapse of the airway during sleep, causing falls in blood oxygen levels and sleep disruption. OSA is associated with memory and concentration problems. Another common condition, dementia, affects over 280,000 Australians....

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