PROJECT SUMMARY: Participation in sport is an extremely popular activity among individuals of all ages. While there are considerable benefits to engaging in sporting activities, one of the potential consequences...
...can protect the brain against the damage associated with PD and partially restore normal movement. Yet it is unclear exactly how this treatment has its protective effects. Most previous work...
...cells was not to replace the neurons that died in the brain following the stroke, but it was other effects, such as factors that the cells secrete in the brain...
...brain, but the controls for that circuitry are higher up- in the cerebral cortex, the conscious part of the brain. When a migraineur encounters one of her trigger factors, some...
Project Summary: Mesial temporal lobe epilepsy is the most common form of adult-onset epilepsy, and patients unresponsive to drug treatments for epilepsy may require surgical removal of brain tissue to...
Project Summary: Parkinson’s disease (PD) is caused by degeneration of dopamine-releasing (dopaminergic) neuronal circuits in the brain. Treatment involves dopaminergic medications, but the effectiveness of these medications is drastically limited...
...proteins in the brain leads to loss of brain cells, thus causing a decline in memory and thinking, and as the disease progresses, a loss of self-care. Currently, there is...
...in the brain- the brainstem. But the controls for that circuitry are higher up- in the cerebral cortex, the conscious part of the brain. Migraine triggers cause neurons in the...
...outcomes. Your donation can fund life-saving research into AVMs and other brain conditions – please give today. Darren’s story Darren was the kind of person who made a lasting impression....
...remove these clots and restore blood flow to the brain, to prevent extensive and permanent damage to brain tissue. “Clot-busting” drugs that dissolve the blood clot (rtPA) are currently used...
...Protein phosphatase 2A (PP2A). However, we have shown that in a number of neurodegenerative diseases, like traumatic brain injury, Alzheimer’s, Parkinson’s and epilepsy, PP2A dysfunction and tau its hyperphosphorylated. This...
...therapeutic targets for drug development. Zika virus causes brain damage mainly by targeting a type of immature brain cells called neural progenitor cells (NPCs), which divide and mature to form...
...the CCM lesion to be in a respectable part of the brain. Due to CCM lesions presenting in variable size, number and locations in the brain, surgical removal is often...
...of what happens to the brain as epilepsy develops over time, which limits the development of better therapies. This project will use advanced optical imaging technology to track brain activity...
...the spinal dura and the CSF leaks out. When this fluid volume is reduced, there is less fluid available to support the normally floating brain inside the skull. The resulting...
...enters the spinal cord and brain where it probably helps to maintain a constant biochemical environment for precise function of brain and spinal cord cells. Despite the critical role of...
...the brain bulges out, often leading the vessel to rupture and blood to leak into the brain and the subarachnoid space (vascularised space between the brain and the skull). This...
...ruptured brain aneurysm when he was just fifteen years old. Over the past two years, his family, friends, and community have been grappling with this devastating loss. In the face...
...safer and more effective in rendering them seizure free.” - Dr Parveen Sagar Watch the full interview with Dr Parveen Sagar below. Project Summary: Focal epilepsy is a neurological disorder...
...around the area of damage in the brain. These nerve cells take on functions of cells that were lost during the stroke. There is growing interest in producing treatments that...
For over 50 years, our primary objective has been to support the highest quality Australian research into brain diseases, disorders, and injuries. The events of 2020 were an unprecedented challenge,...
Project Summary: This project will investigate the mechanisms by which a genetic mutation causes epilepsy. Epilepsy is a very common neurological disorder. People with epilepsy have a tendency to suffer...
...of a biomarker of headache. Migraine is the most prevalent disabling neurological disorder and has a major impact on health resources. Prevalence of migraine is more common than asthma and...
PROJECT SUMMARY: Huntington’s disease (HD) is a fatal disorder involving psychiatric symptoms, dementia and uncontrollable movements. The disease is caused by a ‘genetic stutter’ in a single stretch of repeated...
...suggests damage to the brain’s white matter also plays a key role. White matter contains myelin, a fatty coating that insulates nerve fibres and enables smooth communication between brain cells....
The Brain Foundation is dedicated to funding the next generation of Australian research into brain disorders, diseases, and injuries, with the ultimate goal of advancing diagnoses, treatments, and patient outcomes.