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...which closely mimics the human disease. Our collaborative project will test delivering the missing enzyme to McArdle Disease mice using an adeno-associated virus (or delivering the fetal (brain) version of...

...response using the PKG and the effects of changing medications. We also plan to establish whether the two ICB groups differ according to the brain regions activated during ICB activity...

PROJECT SUMMARY: Traumatic brain injury (TBI) remains one of the leading causes of death, disability, and hospitalization worldwide. TBI has a significant burden of disease within Australia, with TBI-related costs...

Project Summary: Although neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease and motor neuron disease are becoming more and more prevalent in our society, the sad reality is that effective...

Project Summary: The epilepsies are a heterogeneous group of disorders, some inherited and some acquired. The pathogenesis of acquired epilepsies is likely to involve environmental factors and genetic susceptibility. This...

Project Summary: We thank the Brain Foundation for this 2009 research grant award, which will further our clinical studies in the area of cervical dystonia, or involuntary abnormal posturing or...

...the internal environment of the lung is essential for airway function and survival of terrestrial animals. Sensory neurons serve here as the input elements of a complex brain network, which...

...post synaptic apparatus via the second signalling pathway may be a more effective way of treating disorders where reduced synaptic signaling is present, which includes many neurodegenerative disorders such as...

Project Summary: This project will investigate biochemical features of the kinase domain of the Leucine-rich repeat kinase 2 (LRRK2). LRRK2 is a large complex brain protein (2527 amino acids) encoded...

...rapidly translate the most favorable therapeutic combinations to clinical trial. New therapies for medulloblastomas are urgently needed. Medulloblastomas remain the most common malignant brain tumour of childhood, accounting for 20%...

...most common neurological disorders among adults affecting ~4% of individuals over the age of 40 yrs. Approximately 60% of sufferers are unemployed due to disabling shaking. Tremor is characterised by...

Migraine Award funded by Kathleen Toy Bequest To investigate the way painful sensations of migraine might be initiated from the brain. Dr G. A. Lambert and Dr A. S. Zagami...

Stroke Award funded by Frank & Morphyn Young Estate A population-based study of the relation between sub-clinical cerebrovascular disease and brain function in older Tasmanians. Dr Velandai Srikanth Menzies Centre,...

Stroke Award funded by Frank & Morphyn Young Estate Does increased activity of the sodium/calcium exchanger (NCX) ion channel protect the brain from stroke? Associate Professor Neville Knuckey Sir Charles...

PROJECT SUMMARY: One of the main pathological hallmarks of Alzheimer’s disease (AD) and other neurodegenerative diseases called tauopathies is the presence of large protein tangles within brain cells called neurons....

...Synaesthesia is intrinsically linked to neural hyperconnectivity and developmental neural plasticity this study may hold benefits in other areas of rehabilitation, for example stroke recovery and brain training. Progress Report...

...harness the brains capacity for plasticity to optimise functional outcome. The use of music therapy as a non-invasive intervention to improve recovery of movement following neurological injury is gaining momentum....

...5967 PO Box 579 Crows Nest NSW 1585 Suite 21 Regent House 37-43 Alexander Street Crows Nest NSW 2065   Become a member of the Brain Foundation – read more....

PROJECT ABSTRACT: Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique that has potential for clinical utility in neurorehabilitation. However, recent evidence indicates that the responses to tDCS...

...a significant health burden on patients who suffer traumatic brain injury (TBI), which is observable and may be preventable. PTE is often treatment resistant, and associated with significant morbidity and...

...of the funding provided by the Brain Foundation. PROJECT SUMMARY: Epilepsy affects more than 250,000 Australians, with many of these being refractory to conventional therapies. This is a very costly...

Watch Dr Marcus Stoodley accept the research grant award on behalf of Zhenjun Zhao and hear a bit about the project. PROJECT SUMMARY: Brain arteriovenous malformations (AVMs) are abnormalities of...

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