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01 Nov ALZHEIMER’S & OTHER NEURO-DEGENERATIVE DISEASES
...brain. Despite enormous research efforts Alzheimer’s disease still not fully understood. One of the major limitations of understanding Alzheimer’s is the technical difficulty of studying the human brain. Additionally, current...20 Apr Brain Foundation’s response to COVID-19
As COVID-19 continues to spread throughout the world, the Brain Foundation, like all organisations in Australia, is greatly concerned with the impact on all Australians. Our thoughts are with you...
16 Oct Neural Infections
...therapeutic targets for drug development. Zika virus causes brain damage mainly by targeting a type of immature brain cells called neural progenitor cells (NPCs), which divide and mature to form...
16 Oct Neuro-trauma
...also identified increased STING mRNA expression in post-mortem human TBI brain samples, implicating activation of the STING pathway in the human brain after trauma. These data suggest inhibiting type-I IFN...
31 Oct MND / ALS & other Neurodegenerative Diseases
...to use skin cells donated by patients and grow 3D “brain-cells-in-a-dish” or organoids, that can better represent patients’ genetics and mimic the structure, function, and interactions within the human brain...
16 Oct Alzheimer’s and other neuro degenerative diseases
...knowledge of the AD disease process, which is needed to identify new treatment targets. Outcomes: Utilizing human disease-affected autopsy brain tissue cryo-stored in the Queensland Brain Bank (QBB), we expected...
14 Nov Parkinson’s Disease
...brain tissue. Although well-defined clinically the molecular causes of MSA has not yet been elucidated. We recently discovered that hemoglobin genes are highly expressed in the MSA brain. Hemoglobin protein...11 Dec Chiari Malformation
...base of the brain may include the displacement of the lower portion of the brain (cerebellum) and/or brain stem through the opening in the back of the skull (foramen magnum)...
07 Nov Brain Tumours
...nausea and vomiting, seizures, changes in sensation, personality and mood and venous thromboembolism, leading to further complications. Available therapies, including surgery, chemotherapy, whole-brain radiation and anti-angiogenic drugs only interrupt disease...
07 Nov Cerebral Diseases
...of brain cell that is particularly sensitive to death following a stroke. They are the insulating cells of the brain, that wrap up the nerve cells like electrical tape thereby...
19 Oct Neurodegenerative Diseases Award
Project Summary: Huntington’s disease (HD) is a fatal disorder involving psychiatric symptoms, dementia and uncontrollable movements. The disease is caused by a ‘genetic stutter’ in a single stretch of repeated...
31 Oct Chronic Headache and Migraine
...of a biomarker of headache. Migraine is the most prevalent disabling neurological disorder and has a major impact on health resources. Prevalence of migraine is more common than asthma and...
20 Jan Cerebral Diseases
...around the area of damage in the brain. These nerve cells take on functions of cells that were lost during the stroke. There is growing interest in producing treatments that...
19 Jan Congratulations to our 2021 Research Grant Recipients
For over 50 years, our primary objective has been to support the highest quality Australian research into brain diseases, disorders, and injuries. The events of 2020 were an unprecedented challenge,...
27 Jan Parkinson’s Disease Award
Project Summary: Parkinson’s disease (PD) is caused by degeneration of dopamine-releasing (dopaminergic) neuronal circuits in the brain. Treatment involves dopaminergic medications, but the effectiveness of these medications is drastically limited...
31 Oct Alzheimer’s and Other Neuro Degenerative Diseases
...proteins in the brain leads to loss of brain cells, thus causing a decline in memory and thinking, and as the disease progresses, a loss of self-care. Currently, there is...
25 Jan Epilepsy Award
Project Summary: Mesial temporal lobe epilepsy is the most common form of adult-onset epilepsy, and patients unresponsive to drug treatments for epilepsy may require surgical removal of brain tissue to...
19 Dec Kyan’s story: The Impact of Aneurysm
...ruptured brain aneurysm when he was just fifteen years old. Over the past two years, his family, friends, and community have been grappling with this devastating loss. In the face...
31 Oct Cerebral Diseases
...the CCM lesion to be in a respectable part of the brain. Due to CCM lesions presenting in variable size, number and locations in the brain, surgical removal is often...
16 Oct Cerebral Diseases
...these clots and restore blood flow to the brain, to prevent extensive and permanent damage to brain tissue. “Clot-busting” drugs that dissolve the blood clot (rtPA) are currently used to...14 Nov Spinal Cerebrospinal Fluid (CSF) Leak
...the spinal dura and the CSF leaks out. When this fluid volume is reduced, there is less fluid available to support the normally floating brain inside the skull. The resulting...
27 Oct Other (Syringomyelia)
...that CSF enters the spinal cord and brain where it probably helps to maintain a constant biochemical environment for precise function of brain and spinal cord cells. Despite the critical...
The Brain Foundation is dedicated to funding the next generation of Australian research into brain disorders, diseases, and injuries, with the ultimate goal of advancing diagnoses, treatments, and patient outcomes.There is no cure without research.