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...response using the PKG and the effects of changing medications. We also plan to establish whether the two ICB groups differ according to the brain regions activated during ICB activity...

PROJECT SUMMARY: Traumatic brain injury (TBI) remains one of the leading causes of death, disability, and hospitalization worldwide. TBI has a significant burden of disease within Australia, with TBI-related costs...

Project Summary: Although neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease and motor neuron disease are becoming more and more prevalent in our society, the sad reality is that effective...

Project Summary: The epilepsies are a heterogeneous group of disorders, some inherited and some acquired. The pathogenesis of acquired epilepsies is likely to involve environmental factors and genetic susceptibility. This...

Project Summary: We thank the Brain Foundation for this 2009 research grant award, which will further our clinical studies in the area of cervical dystonia, or involuntary abnormal posturing or...

...post synaptic apparatus via the second signalling pathway may be a more effective way of treating disorders where reduced synaptic signaling is present, which includes many neurodegenerative disorders such as...

Project Summary: This project will investigate biochemical features of the kinase domain of the Leucine-rich repeat kinase 2 (LRRK2). LRRK2 is a large complex brain protein (2527 amino acids) encoded...

...rapidly translate the most favorable therapeutic combinations to clinical trial. New therapies for medulloblastomas are urgently needed. Medulloblastomas remain the most common malignant brain tumour of childhood, accounting for 20%...
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