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...that microglia (brain immune cells) are an integral part of human brain tumours and our aims are to understand if these microglia promote or inhibit tumour growth? In addition, we...

...national organisations will have state branches that help facilitate this, such as: Brain Injury Australia (brain injuries include traumatic brain injuries, stroke, infection, and degenerative diseases) Brain Tumour Alliance Australia...

Project Summary: Today in Australia, 4 people will be diagnosed with a brain tumour. This equates to 1600 tumours in Australia each year. These may be benign or malignant. Present...

...high activity within the tumour, but not normal brain, makes it an ideal potential therapeutic target. With the help of the brain foundation we aim to investigate the effects of...

...tumours will uncover new targets for brain tumour therapies in the future, and also point to potential new blood tests for the diagnosis or monitoring of brain tumours. Final Report...

PROJECT SUMMARY: This project seeks to investigate a potential therapeutic antibody (MAR-1) that can limit the damage of traumatic brain injury. Traumatic brain injury (TBI) represents the major cause of...

...within the brain (cerebral haemorrhage), or (c) rupture of a blood vessel into the space surrounding the brain (subarachnoid haemorrhage). About 50% of patients who subsequently have a stroke due...

...cells) can provide the answer. These stem cells can be used to make 3D cortical brain organoids, or ‘mini-brains’. These ‘mini-brains’ contain the same genetic make-up as the patient they...

...well as neuropsychiatric disorders. Notably, T. gondii infection also results in inflammation in the brain. Traumatic brain injury (TBI) and stroke are common forms of brain injury that affect millions...

...in a large number of well-characterised cases collected through the Sydney Brain Bank. Brain donors are recruited through longitudinal, prospective brain donor programs with an interest in ageing and neurodegeneration....

...blood markers that can differentiate between patients with brain tumours and healthy controls with over 99% accuracy. We plan to validate this panel during the monitoring of patients with brain...

...of the funding provided by the Brain Foundation. PROJECT SUMMARY: Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease affecting the brain and spinal cord. There are over 25,000 Australians...

...brain is injured (from e.g. trauma, stroke or bleeding around the brain) swelling occurs. Because the skull is basically a ‘closed box’ this swelling can cause a pressure rise. This...

...adults worldwide. Neuroprotective treatments to reduce brain damage associated with TBI are currently lacking, which makes developing effective treatments of paramount importance. Any treatment that minimises brain injury associated with...

Project Summary: Brain tumours are the leading cause of cancer related death and disability in children. The Royal Children’s Cancer research laboratory is focused on improving our understanding of medulloblastoma,...

...accommodate the swollen brain and although life saving, it is highly invasive and potentially risky. As a result, alternate treatments for brain swelling that address the cause of the swelling...

PROJECT SUMMARY: In Australia, brain cancer is the leading cause of cancer-associated death for adults under the age of 40 and children under the age of 10, with one person...
Brain FoundationThe Brain Foundation is the largest, independent funder of brain and spinal injury research in Australia. We believe research is the pathway to recovery.
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